Alterations of Circulating Endothelial Cell and Endothelial Progenitor Cell Counts around the Ovulation

Endothelial Progenitor Cell Dysfunction in Polycystic Ovary Syndrome: Implications for The Genesis of Cardiovascular Diseases

Circulating endothelial progenitor cells in adults with sickle cell disease

How, then, are we to make progress, when experiments cannot be done in humans, and we cannot trust the results from mice? The answer is, thoughtfully. As Drs Keogh and Menache point out, genes do not work individually or in linear pathways, but rather in networks. We can use mice to work out the links in these networks, while understanding that the relative strengths of the connections are diff...

Radiation-induced expression of platelet endothelial cell adhesion molecule-1 in cerebral endothelial cells

Background: Radiation-induced molecular changes on the endothelial surface of brain arteriovenous malformations (AVM) may be used as markers for specific vascular targeting agents. In this study, we examined the level of expression of platelet endothelial cell adhesion molecule-1 (PECAM-1) on brain endothelial cell surface after radiation treatment, with the aim of targeting the radiation-induc...

Altered endothelial reparation and diabetes-Induced endothelial progenitor cell dysfunction

Diabetes mellitus (DM) is considered a leading cause of premature cardiovascular (CV) mortality and morbidity in general population and in individuals with known CV disease. Recent animal and clinical studies have shown that reduced number and weak function of endothelial progenitor cells (EPCs) may not only indicate to higher CV risk, but contribute to the impaired heart and vessels reparation...

Kinin Receptors and Endothelial Progenitor Cell Dysfunction

The field of progenitor cell therapy appears to be poised to transform the management of many cardiovascular diseases. In particular, the use of bone marrow-derived mononuclear cells (BM-MNCs) and endothelial progenitor cells (EPCs) have shown indications of improved cardiac function post–myocardial infarction (MI), with a recent metaanalysis showing a highly significant mean improvement in glo...